Covariate-adaptive randomization represents an advanced methodology in the design of clinical trials, ensuring a balanced distribution of prognostic factors among treatment groups. This approach ...
"Covariate adjustment" in the randomized trial context refers to an estimator of the average treatment effect that adjusts for chance imbalances between study arms in baseline variables (called ...
(OXFORDSHIRE, England & CONSHOHOCKEN, Penn. & ROCKVILLE, Md., US, 18 June 2024) Immunocore Holdings plc (Nasdaq: IMCR) (“Immunocore” or the“Company”) , a commercial-stage biotechnology company ...
Memantine treatment was more efficacious than placebo in improving social functioning in youths with autism spectrum disorder ...
Randomized Phase II Study of Concurrent Versus Sequential Pembrolizumab in Combination With Chemoradiation in Locally Advanced Head and Neck Cancer Newly diagnosed patients with cT2-4N0-2M0 HNC were ...
January 30, 2012 — Long-term results from a brain tumor trial show that a chromosomal abnormality — 1p19q codeletion — plays a crucial role in the outcome of patients with oligodendrogliomas. The ...
Trials should assess overall survival to evaluate potential harm, with crossover limited to avoid confounding treatment ...
Semaglutide at a dose of 2.4 mg has established weight-loss and cardiovascular benefits, and cagrilintide at a dose of 2.4 mg has shown promising results in early-phase trials; the efficacy of the ...
In a cohort of men trying to conceive, the use of antioxidants did not significantly improve pregnancy rates compared to a placebo. 2. In the “optimal treatment window,” pregnancy rates were ...
USA: A large multicenter randomized clinical trial has found that administering budesonide mixed with surfactant did not ...
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