Five Chiefs players were injured in Kansas City's loss to the Seattle Seahawks in Week 2 of the 2025 NFL preseason.

The Chiefs fell to the Seahawks 33-16 in the second preseason game on a rainy night in Seattle. Andy Reid followed through on his suggestion earlier in the week that key players like Patrick Mahomes and Chris Jones wouldn’t play. The offense, led by Gardner Minshew, moved the ball and punched in a touchdown on one of two possessions.

Seattle has rushed for 174 yards as a team on 22 total carries. The Seahawks are outright dominating the Chiefs in preseason Week 2. The fans demanded More Bobo, and by golly they're getting More Bobo! Drew Lock found Jake Bobo for yet another 12-yard touchdown strike to increase Seattle's lead to 23-7, which they took into halftime.