Protein kinase CK2 (formerly known as casein kinase II) has been viewed traditionally as a stable heterotetrameric complex, but new analytical techniques are bringing a different picture into focus.

Protein serine-threonine kinase casein kinase II (CK2) is involved in a myriad of cellular processes including cell growth and proliferation through its phosphorylation of hundreds of substrates, yet ...

1 Department of Biochemistry and Molecular Biology, Drexel University College of Medicine, Philadelphia, PA, United States 2 Department of Cancer Biology, Perelman School of Medicine, University of ...

Protein kinase CK2 ('casein kinase II') has traditionally been classified as a messenger-independent protein serine/threonine kinase that is typically found in tetrameric complexes consisting of two ...

CK2 activity and stability are believed to be regulated in part by holoenzyme formation via a self-assembly mechanism and by phosphorylation. Phosphorylation by p34 cdc2 of the catalytic α subunit at ...

G protein-coupled receptors (GPCRs) regulate the activity of virtually all cell types including pancreatic β-cells. β-Cell M 3 muscarinic receptors (M3Rs) play an essential role in maintaining proper ...

Magnaporthe oryzae (Mo) is a model pathogen causing rice blast resulting in yield and economic losses world-wide. CK2 is a constitutively active, serine/threonine kinase in eukaryotes, having a wide ...

The protein kinase CK2 is involved in a wide range of biological processes and cellular functions, including inflammatory responses and pathologies associated with inflammation. CD8+ T cells, also ...

Upon nutritional stress, the metabolic status of cells is changed by nutrient signaling pathways to ensure survival. Altered metabolism by nutrient signaling pathways has been suggested to influence ...