Although naturally occurring proteins form stable defined tertiary structures, it is well known that many proteins with non-natural sequences have unstructured conformations 1,2. This suggests that ...

Figure 1: The permutation-by-duplication model is presumed to account for the evolution of various classes of DNA methyltransferases. Figure 2: Reproducing the first two steps of the ...

Using a technique called circular permutation, researchers at the University of California Berkeley have created a new suite of Cas9 variants called Cas9-CPs, which will simplify design of Cas9-fusion ...

Chromosome engineering is a major focus in the fields of systems biology, genetics, synthetic biology, and the functional analysis of genomes. Here, we describe the "telomerator," a new synthetic ...

Using a technique called circular permutation, researchers at the University of California Berkeley have created a new suite of Cas9 variants called Cas9-CPs, which will simplify design of Cas9-fusion ...

This is a preview. Log in through your library . Abstract A simple method is provided for testing uniformity on the circle that allows dependence among repeated angular measurements on the same ...