Students model how scientists use DNA microarrays to determine levels of gene expression in breast cancer patients, and then choose treatments based on what they learn. Normal-functioning DNA codes ...
Persistent Doubts about Reproducibility and Compatability of Data Are Being Overcome One of the hottest research tools these days within the academic, biotech, and pharma communities is DNA ...
Most pharmaceuticals sold today have their origin in a biochemistry laboratory. Drug discovery has traditionally started with a biochemical pathway implicated in a pathophysiological process. An ...
BUFFALO, N.Y. -- A multidisciplinary team of pharmaceutics and computer-science researchers at the University at Buffalo, one of very few teams in the nation applying DNA microarray technology in ...
DNA microarray chips enable the parallel investigation of a given sample concerning the presence and amount of specific DNA sequences within that sample. Whereas today such chips utilize optical ...
Gene amplifications and deletions frequently have pathogenetic roles in cancer. 30,000 radiation-hybrid mapped cDNAs provide a genomic resource to map these lesions with high resolution. We developed ...
An important question that arises when caring for patients referred for phase I clinical trials is, if one studied the patients’ tumors carefully enough, would there be targets in those patients’ ...
Hitachi Software Engineering Co. Ltd. and a Japanese venture DNA Chip Research Inc. have jointly developed DNA (deoxyribonucleic acid) chips that carry about the same number of genes as the full human ...