Metacaspases, ancestral homologues of the caspase family, are pivotal cysteine proteases found in a wide range of unicellular organisms, including yeasts, algae, and phytoplankton. These enzymes ...

The delicate balance between cell death and regeneration is crucial for human health and longevity. Most mechanisms involved in programmed cell death (PCD) play a key role in normal tissue renewal and ...

A team of researchers at the University of Cologne's Center for Biochemistry, together with the Bambino Gesù Pediatric Hospital in Rome, Italy, have discovered a fundamental biological mechanism that ...