Covariate-adaptive randomization represents an advanced methodology in the design of clinical trials, ensuring a balanced distribution of prognostic factors among treatment groups. This approach ...

"Covariate adjustment" in the randomized trial context refers to an estimator of the average treatment effect that adjusts for chance imbalances between study arms in baseline variables (called ...

Memantine treatment was more efficacious than placebo in improving social functioning in youths with autism spectrum disorder ...

Lu]Lu-PSMA-617 radiopharmaceutical therapy has been approved for the treatment of men with metastatic castration-resistant ...

In a cohort of men trying to conceive, the use of antioxidants did not significantly improve pregnancy rates compared to a placebo. 2. In the “optimal treatment window,” pregnancy rates were ...

January 30, 2012 — Long-term results from a brain tumor trial show that a chromosomal abnormality — 1p19q codeletion — plays a crucial role in the outcome of patients with oligodendrogliomas. The ...

USA: A large multicenter randomized clinical trial has found that administering budesonide mixed with surfactant did not ...

A large Dutch randomized clinical trial (SUMMER) found that a widely marketed antioxidant supplement (Impryl) did not improve ...

The past 12 months have been huge for cannabis research, with hundred of studies and dozens of rigorously designed clinical ...