JAK2 belongs to the Janus family of cytoplasmic tyrosine kinases (JAK1–JAK3, TYK2) and functions as a crucial mediator of signaling for hematopoietic cytokines and hormones such as erythropoietin (Epo ...
Regulated protein transport between the cell surface and distinct intracellular compartments of the endo- and exocytic apparatus is a crucial determinant of cellular function. Proper protein ...
Steven McKnight and Dirk Görlich received the Albert Lasker Basic Medical Research Award for their work on the role of disordered proteins in cell biology.
Hsp70 chaperone systems are very versatile machines present in nearly all living organisms and in nearly all intracellular compartments. They function in many fundamental processes through their ...
In a recent study posted to the bioRxiv* preprint server, researchers explored the role of the N-terminal domain (NTD) of the severe acute respiratory syndrome coronavirus 2 (SARS-COV-2) spike (S) ...
The LATERAL ORGAN BOUNDARIES (LOB) DOMAIN (LBD) gene family encodes plant-specific transcriptional regulators functioning in organ development. In a screen of Arabidopsis (Arabidopsis thaliana) ...
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