Figure 1: Dynamic ligand binding dictates partial agonism: model, predictions and chemical tools. Our findings revise the concept of partial agonism at GPCRs. We show that bipharmacophoric ligands ...

Reversible covalent bonding is often used for the creation of novel supramolecular structures, multi-component assemblies and sensing ensembles. Despite the remarkable success of dynamic covalent ...

The clinical need for ultrasensitive molecular analysis has motivated the development of several endpoint-assay technologies capable of single-molecule readout. These endpoint assays are now primarily ...

The actin cytoskeleton coordinates numerous cellular processes required for plant development. The functions of this network are intricately linked to its dynamic arrangement, and thus progress in ...