A new artificial intelligence tool can predict the functions of enzymes based on their amino acid sequences, even when the enzymes are unstudied or poorly understood. Researchers said the AI tool, ...

Chemical structure for thiamine pyrophosphate and protein structure of transketolase. Thiamine pyrophosphate cofactor in yellow and xylulose 5-phosphate substrate in black. Credit: Thomas ...

Researchers participating in the Enzyme Function Initiative (EFI) have used a computationally rich metabolite-docking strategy to sift through a protein’s potential metabolic partners and predict its ...

The collection of proteins within a cell determines its health and function. Proteins are responsible for nearly every task of cellular life, including cell shape and inner organization, product ...

Cytochrome P450 enzymes constitute a superfamily of haem-containing proteins that catalyse the oxidation of a wide range of exogenous and endogenous compounds. Their function is fundamental to the ...

Enzymes help with specific functions that are vital to the operation and overall health of the body. They help speed up chemical reactions in the human body. They are essential for respiration, ...

While E. coli is one of the most studied organisms, the function of 30% of proteins that make up E. coli has not yet been clearly revealed. For this, an artificial intelligence was used to discover ...

A new technique could make it easier to target and inhibit specific enzymes and other proteins in cells and to turn that regulation on and off at will with light. The approach provides researchers ...

Researchers have worked out the exact function of an enzyme that is critical for normal muscle structure and is involved in several muscular dystrophies. The findings could be used to develop rapid, ...

Dynamin 1, thought to be essential to all synaptic function, acts more subtly. A key cellular enzyme called dynamin 1, thought to be essential to all synaptic transmission, is in fact not always ...

Researchers at Freiburg University discover new functions of the widely disseminated, yet little understood ENDOU enzyme. The family of ENDOU enzymes is found in most organisms, yet its functions are ...