Extracytoplasmic function (ECF) sigma factors are a distinct subset of sigma factors that enable bacteria to respond robustly to a myriad of environmental challenges. By directing RNA polymerase to ...
Researchers from the Max Planck Institute for Terrestrial Microbiology in Marburg have described a previously unrecognized mechanism of bacterial transcriptional regulation that is obviously ...
Sequence-specific, DNA-binding TFs are the major regulators of cell identity and cell physiology. As examples, expression of select TFs can revert differentiated cells back to a pluripotent state and ...
The system of long noncoding RNA (lncRNA)–mediated transcriptional interference that represses fission yeast phosphate homoeostasis gene pho1 provides a sensitive readout of genetic influences on ...
Eukaryotes respond to amino acid starvation by enhancing the translation of mRNAs encoding b-ZIP family transcription factors (GCN4 in Saccharomyces cerevisiae and ATF4 in mammals), which launch ...
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