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Flow cytometry was thrust into the spotlight by the AIDS epidemic in the 1980s as it provides a quick and accurate way to count CD4 + and CD8 + T cells in HIV-infected patients.
We developed a carboxyfluorescein succinimidyl ester (CFSE)-based flow-cytometric assay that can detect different subsets of vaccinia-specific T cells capable of both antigen-specific expansion and ...
Flow cytometry is an effective method for identifying rare cells such as CD4 T cells amongst mixed cell-type populations. Download this application note to discover how the Attune™ NxT Flow Cytometer: ...
As flow cytometric technology advanced to 18 colors, staining for intracellular cytokines and transcription factors confirmed a surface marker phenotype with functional markers. General Immune Subsets ...
Flow cytometry has long been used in cell counting and cell sorting. More recent applications include biomarker detection, protein engineering, cell signaling, pathway screening, and systems ...
Flow cytometry is a powerful technique for the analysis of multiple parameters of individual cells within heterogeneous populations. Flow cytometers are used in a broad range of applications including ...
While flow cytometry can reliably assess surface and intracellular marker expression within small cell populations, it does not provide any information on protein localization.
Flow cytometry has been utilized at each stage of the drug discovery process, from target identification to lead development.
An AI-enabled microfluidic cytometer could make flow cytometry more accessible, affordable and faster. A research team from George R Brown School of Engineering and Computing (Rice University; TX, USA ...
In this case study, scientists used flow cytometry as a means of determining platelet function in neonates.
Cell proliferation may be assessed by flow cytometry. Cell are labelled with the dye CFDA,SE which spontaneously and irreversibly couples to both intracellular and cell surface proteins. When cells ...