I am trying to create a 5 day chart of Intraday Stock data using mplfinance. From Open to Close only, no data gaps. I can get a chart to save and/or show but am struggling with formatting the grid ...

You can place a label (title) the beside the y-axis using ylabel kwarg. Mplfinance does not provide direct access to the x-axis label because it is always time/date, however if you want to label it ...