The deubiquitinase USP17LA negatively regulates T-cell activation and attenuates anti-tumor immunity
USP17LA loss enhances T-cell function and anti-tumor activity in murine tumor models. Usp17la-deficient T cells exhibit ...
Identification of type 2 diabetes- and obesity-associated human β-cells using deep transfer learning
Deep transfer learning methodologies reveal hidden heterogeneity in β-cells driven by type 2 diabetes and obesity.
Researchers from the University of California San Diego Sanford Stem Cell Institute have discovered that spaceflight accelerates the aging of human hematopoietic stem and progenitor cells (HSPCs), ...
Uptake of cell-free chromatin particles released from dying cells and carrying non-coding DNA could redefine mammalian genomics.
When someone has a stroke—a leading worldwide cause of death and disability—time is of the essence. Almost nine out of 10 ...
A USC Stem Cell-led research team has achieved a major step forward in the effort to build mouse and human synthetic kidneys.
Purkinje cells, the neurons of the cerebellum, appear to die in an organized pattern, overturning previous beliefs that ...
Just as life pulsates in big vibrant cities, it also prospers in crowded environments inside cells. The interior of cells is ...
Per- and polyfluoroalkyl substances (PFAS), manmade chemicals that accumulate in the body over time, have been linked to liver disease and cancer, but it is not yet clear how they cause damage.
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