The lactose operon regulation in Escherichia coli is a primary model of phenotypic switching, reminiscent of cell fate determination in higher organisms. Under conditions of bistability, an isogenic ...

Repression of transcription of the Escherichia coli Lac operon by the Lac repressor (LacR) is accompanied by the simultaneous binding of LacR to two operators and the formation of a DNA loop. A ...

Mathematical models and computer simulations of genetic networks have demonstrated collective behaviors (commonly called systems, or emergent properties) that were not apparent from examination of the ...

Abstract: Gene regulation is an essential process for cell development, having a profound effect in dictating cell functions. Bacterial genes are often regulated through inducible systems like the Lac ...

The traditional view, as supported by Crasnier-Mednansky, places cAMP–CRP at the centre of CCR. This view is plausible, as it links glucose availability, the phosphorylation state of EIIA Crr and the ...

This is a preview. Log in through your library . Abstract We have cloned a DNA fragment harboring the genes for ribosomal proteins L2, L4, and L23 on a plasmid vector that contains a lac operator and ...