HDAds provide stable, long-term transgene expression in small and large animal models without chronic toxicity for liver-directed gene therapy. High vector doses are required for efficient hepatocyte ...

In combination with transgenic mouse lines expressing Cre or Flp recombinases in defined cell types, recombinase-dependent adeno-associated viruses (AAVs) have become the tool of choice for localized ...

In this paper, we study the precise large deviations of sums of two-dimensional random vectors with two dependent and real-valued components. In the presence of heavy tails, we obtain some uniformly ...