We propose the warped linear mixed model (WarpedLMM), a principled generalization of the standard LMM that allows to fit phenotype transformations while performing genetic analyses.

Sanjoy K. Sinha, Robust Analysis of Generalized Linear Mixed Models, Journal of the American Statistical Association, Vol. 99, No. 466 (Apr., 2004), pp. 451-460 ...

However, the utility of linear (mixed) models in the context of meta-analysis of GWAS of binary phenotypes has not been previously explored.

Then we describe three common applications of the linear mixed model in contemporary human genetics: association testing (pathways analysis or rare variants association tests), genomic heritability ...

Just as PROC GLM is the flagship procedure for fixed-effect linear models, the MIXED procedure is the flagship procedure for random- and mixed-effect linear models. PROC MIXED fits a variety of mixed ...