Macrophages rely on lysosomes to balance microbial killing with self-protection, generating reactive oxygen and nitrogen ...

Acute kidney injury (AKI) is associated with a poor prognosis, and no effective treatment has been established to date. Understanding the mechanisms that prevent the progression of AKI is crucial. In ...

An innovative combination of methods to identify and study how macrophages function could potentially revolutionize the diagnosis and treatment of various diseases. Macrophages play a critical role in ...

Macrophages and other immune cells are the natural frontline immune warriors of our body, defending the body against invading pathogens and cancer cells. Yet despite their innate "combat" capabilities ...

New research from Indiana University School of Medicine scientists has revealed that a well-known cancer-fighting gene also ...

Ryan Allen, an assistant professor of physiology and cell biology at the UAMS, will share a current project from his lab dedicated to developing a drug-responsive mouse model of atherosclerosis.

Myc dysregulation in activated macrophages impairs antioxidant defenses, locking them in a vicious cycle that amplifies type I interferon signaling, driving hyperinflammation and immunosuppression.

Disrupted function of 'cleaning cells' in the body may help to explain why some people with obesity develop type 2 diabetes, while others do not. A study describes this newly discovered mechanism.

Macomics Ltd, a leader in macrophage drug discovery, announces that it has validated its ENIGMAC™ platform in neurodegeneration and neuroinflammation applications. Macomics’ ENIGMAC drug discovery ...

ATS 2025, San Francisco – Microplastics are ubiquitous in the environment, and we all routinely inhale these tiny pollutants. Now new research published at the ATS 2025 International Conference has ...