Memory formation and maintenance fundamentally rely on intricate molecular processes that regulate synaptic strength. Central to this phenomenon is synaptic plasticity – the capacity of neural ...

A new study explores the structural basis of memory formation in the mouse brain, revealing how neurons reorganize their connections via multi-synaptic boutons. The findings challenge traditional ...

Computational models show that even subtle modifications in the synaptic protein CaMKII completely alter the resulting protein structures. Given how the formation and stability of these structures ...

Neurons have variable levels of chromatin compaction, shown as different shades of red. The less compact a neuron, the more likely it is to be recruited into the memory trace (green). When we form a ...

Bioluminescent RNA lanterns have revolutionized the way researchers track RNA activity within living organisms. In a groundbreaking study, scientists at the University of California, Irvine (UCI) ...

Brain cells known as astrocytes play a prominent part in tuning the changes in neuronal activity that enable memories to be stored ...

When a new memory forms the brain undergoes physical and functional changes known collectively as a “memory trace.” This memory trace represents the specific patterns of neuronal activity and ...

In a study supported by the National Institutes of Health (NIH), researchers revealed the structural underpinnings of memory formation across a broad network of neurons in the mouse brain. This work ...