It is traditionally assumed that the random effects in mixed models follow a multivariate normal distribution, making likelihood-based inferences more feasible theoretically and computationally.

We consider selecting both fixed and random effects in a general class of mixed effects models using maximum penalized likelihood (MPL) estimation along with the smoothly clipped absolute deviation ...

Severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2) infection is usually diagnosed via reverse transcription PCR or RT-PCR, but this method is far from perfect. According to one review, ...