Multiple sequence alignment is a difficult computational problem. There have been compelling pleas for methods to assess whole-genome multiple sequence alignments and compare the alignments ...

Tree and sequence alignment visualizations have a long history. Evolutionary tree diagrams can be found in even the earliest descriptions of evolution, and their visualization still plays a key ...

The dependence of the results of molecular phylogenetic sequence analysis (both alignment and cladogram construction) on variation in analytical parameters is examined. Phylogenetic analyses of ...

Multiple observations of homologous protein or nucleic acid sequences from different organisms are often available. But because mutations and sequence errors misalign these data, multiple sequence ...

Edgar calls his new algorithm MUSCLE (multiple sequence comparison by log expectation). MUSCLE uses a log expectation score to control progressive alignment of the input amino acid sequences. This ...