Replicative DNA polymerases (Pol) function with a sliding clamp and their proofreading exonuclease provides high fidelity. Thus, the study of the proofreading mechanism must both contain the Pol–clamp ...

The polymerase of RNA viruses lacks the proofreading capacity found in the polymerase of DNA viruses, leading to high error rates and low replicative fidelity ...

To fight infections and cancer, T cells must selectively recognize low levels of foreign peptides from pathogens or cancer cells, but the mechanisms that enable these properties remain unclear. Using ...

The proofreading exonuclease domains of the replicative DNA polymerases Pol δ and Pol ε perform an essential function in ensuring accurate DNA replication by proofreading and removing mispaired bases ...

The success and popularity of a book, on a great scale, depends on the editor of the book. An editor is the nicest man who without any so called credibility, performs ...