I am hoping there are some Python and Fabric gurus here, I have my Python program connecting to my cisco devices with Fabric just fine except I can't execute commands that require configuration ...

You're taking a new programming class this fall, and you don't know anything about code. Python is taught widely in schools, and it's one of the most loved programming languages because it's simple.

This allows you to instantly type and execute Python commands, just like you would when running Python on your PC. You can also redirect the REPL to any of the UARTs on the pyboard.