python -m timeit -s "import hashlib" "h = hashlib.sha256 (); h.update (b'x' * 32); h.digest ()" 500000 loops, best of 5: 465 nsec per loop The original context was to experiment with key derivation ...

You'd need to put the broken DLL in syswow64 for 32 bit. This is just standard DLL-hell though, no one but Microsoft should put libraries in that folder and the software doing this is broken and ...