Bodybuilders and cellular mechanisms agree generating protein is a heavy lift. To complete the task, cells rely on complexes called spliceosomes. These molecular machines snip extra bits out of our ...
Nano-tRNAseq is based on nanopore sequencing, a technology that can directly sequence individual RNA molecules by passing them through a small pore. Each of the nucleotides that compose an RNA ...
We study regulation of gene expression by the minor spliceosome. This parallel pre-mRNA splicing machinery functions during the nuclear RNA processing phase and regulates cellular mRNA levels. We ...
A group of Australian scientists has uncovered a new way to fight some of the toughest cancers by targeting an overlooked cellular process called minor splicing. This tiny but vital mechanism turns ...
v. 1. Synthesis and purification of RNA substrates / Benoit Chabot -- Characterization of RNA / Paula J. Grabowski -- Splicing of mRNA precursors in mammalian cells / Ian C. Eperon, Adrian R. Krainer ...
Researchers at the University of Barcelona reveal that RTP801, a protein elevated in Alzheimer’s patients, disrupts RNA processing and protein synthesis, exacerbating cognitive decline. This discovery ...
A study from the Walter and Eliza Hall Institute of Medical Research (WEHI) has found that blocking a specialised RNA process called minor splicing slows tumour growth in animal models of liver, lung ...
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