Ribosomes are fundamental molecular machines that translate mRNA sequences into polypeptides, ensuring the proper synthesis of proteins essential to cellular function. However, the fidelity of protein ...

Bacterial ribosomes are central to protein synthesis, and their regulation is vital for adaptation to environmental stresses. Under conditions such as nutrient deprivation, cold shock or hypoxia, ...

Scientists report a method for stable attachment of peptides to tRNAs, which has allowed them to gain new fundamental insights into ribosome function by determining the atomic-level structures of ...

Researchers at Children's Hospital of Philadelphia (CHOP) have identified genes responsible for hematopoietic stem cell (HSC) regeneration via the assembly of the ribosome, the protein factories in ...

Inside tiny cellular machines called ribosomes, chains of genetic material called messenger RNAs (mRNAs) are matched with the corresponding transfer RNAs (tRNAs) to create sequences of amino acids ...

Space to play or pause, M to mute, left and right arrows to seek, up and down arrows for volume. Robyn Williams: Everyone in the following program has a genius-level IQ, except of course for me. I am ...

Aging leads to a decline in cellular fitness and loss of optimal protein function. Many age-related ailments, including Alzheimer’s and Parkinson’s diseases, are caused by protein aggregation, a ...

“It’s a really clever paper and there’s a huge body of work that underlies it,” said molecular biologist Harry Noller of the University of California, Santa Cruz, who was not involved in the work. “It ...

Northwestern Medicine scientists have uncovered new details about how poxvirus hijacks its host's protein synthesis machinery to multiply and spread, according to a study published in Nature ...

This is a preview. Log in through your library . Abstract Fanconi anemia (FA) is a disease of DNA repair characterized by bone marrow failure and a reduced ability to remove DNA interstrand ...