A continuous region of coding sequence can be PCR amplified using a 5′ primer possessing a polymerase binding site and a translation initiation site in-frame with the 5′ end of the test sequence. The ...

The process of deciphering information conveyed by neurons in the human brain is known as neural coding. Conventionally, it has been done by considering how neurons change their rate of firing signals ...

Using STING-seq, short for systematic targeting and inhibition of noncoding GWAS loci with single cell sequencing, Sanjana and his team identified promising sequence variants linked to various ...

T-cell inflamed phenotype gene expression signatures to predict clinical benefit from pembrolizumab across multiple tumor types. This is an ASCO Meeting Abstract from the 2016 ASCO Annual Meeting I.

RNA vaccines are a new class of vaccines that are composed of an mRNA sequence coding for a pathogen-specific protein (antigen). Once expressed in the body, the target antigen is recognized by the ...

The U.S. Food and Drug Administration (FDA) has granted orphan drug status to NS-051/NCNP-04, an exon-skipping therapy ...