The use of large genomic data sets in phylogenetics has highlighted extensive topological variation across genes. Much of this discordance is assumed to result from biological processes. However, ...

Data sources Six databases, six trial registries and prior systematic reviews. Forward and backward citation tracking was employed. Eligibility criteria Randomised controlled trials that compared ...

In single-arm trials, false-positive error rates (type I error) were 2 to 4 times those projected when modest drift or patient selection effects (eg, 5% absolute ...