Considerable efforts have been made over the years to resolve the key issues of stability and delivery of RNA-based therapeutics. For several years after Crick (1) first described the genetic role of ...

CRISPR-Cas systems are adaptive immune systems found in prokaryotes that defend against invading nucleic acids through CRISPR ...

RNA-binding proteins (RBPs) are central regulators of post-transcriptional gene expression. They modulate key aspects of mRNA metabolism—such as splicing, ...

Ribonucleic acid, also called RNA, is a molecule present in all living cells. It plays a critical role in transmitting genetic instructions from DNA and creating proteins. With the power to execute a ...

Researchers at Arizona State University’s (ASU) School of Molecular Sciences and the Biodesign Institute’s Center for the Mechanism of Evolution have discovered an unprecedented pathway producing ...

Genes contain instructions for protein production, and the central dogma of biology states that this information flows from DNA to RNA to proteins. However, only about 2% of the human genome actually ...

Researchers from the Icahn School of Medicine at Mount Sinai have shed valuable light on the nuanced functions and intricate regulatory methods of RNA editing, a critical mechanism underlying brain ...

The better we understand cellular processes such as RNA regulation, the better molecular therapies can be developed. Until now, it has been especially difficult to track the regulation of non-coding ...