Ribonucleic acid, also called RNA, is a molecule present in all living cells. It plays a critical role in transmitting genetic instructions from DNA and creating proteins. With the power to execute a ...
RNA-binding proteins (RBPs) are central regulators of post-transcriptional gene expression. They modulate key aspects of mRNA metabolism—such as splicing, ...
Researchers from the Icahn School of Medicine at Mount Sinai have shed valuable light on the nuanced functions and intricate regulatory methods of RNA editing, a critical mechanism underlying brain ...
The better we understand cellular processes such as RNA regulation, the better molecular therapies can be developed. Until now, it has been especially difficult to track the regulation of non-coding ...
Researchers at Arizona State University’s (ASU) School of Molecular Sciences and the Biodesign Institute’s Center for the Mechanism of Evolution have discovered an unprecedented pathway producing ...
A new study has discovered an unprecedented pathway producing telomerase RNA from a protein-coding messenger RNA (mRNA). For the very first time, a study led by Julian Chen and his group in Arizona ...
A new study reveals ribosomal RNA (rRNA) may play a surprising role beyond protein production. Researchers found unique rRNA ...
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CRISPR Reveals Hidden Functions of Noncoding RNA
Genes contain instructions for protein production, and the central dogma of biology states that this information flows from DNA to RNA to proteins. However, only about 2% of the human genome actually ...
The natural RNAi mechanism can be directed by either short interfering RNA (siRNA) or microRNA (miRNA). 1 There are four key steps in the RNAi pathway. When miRNA acts as the guide for RNAi, only a ...
As a PhD student at the University of Münster in the early 2000s, Sven Diederichs would bike three kilometers each morning to a compact lab in a brick building on the hospital campus. There, he’d ...
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