Nature

CTF/NF1 transcription factors act as potent genetic insulators for integrating gene transfer vectors

Gene transfer-based therapeutic approaches have greatly benefited from the ability of some viral vectors to efficiently integrate within the cell genome and ensure persistent transmission of newly ...
Nature

Retroviral vector insertions in T-lymphocytes used for suicide gene therapy occur in gene groups with specific molecular functions

Graft-versus-host disease (GvHD) is a severe complication in the context of allogeneic stem cell transplantation and adoptive immunotherapy. The transfer of a suicide gene into donor T-lymphocytes ...
JSTOR Daily

Foamy Virus Vector Integration Sites in Normal Human Cells

Foamy viruses (FVs) or spumaviruses are retroviruses that have been developed as vectors, but their integration patterns have not been described. We have performed a large-scale analysis of FV ...
Yahoo Finance

Hazelcast Adds Vector Search, Unveils Core Architecture for AI Integration

Hazelcast Platform 5.5 delivers advanced query, compute capabilities to power AI and mission-critical applications PALO ALTO, Calif., July 30, 2024 /PRNewswire/ -- Hazelcast, Inc. is announcing the ...