Microsoft recommends replacing relic from old .NET Framework with Blazor, but you can still do ASP.NET Web Forms apps in Visual Studio 2022 if you want to, with a couple tweaks.

Microsoft announced that when using Visual Studio 2022 and starting the app with the debugger, Hot Reload works with most app frameworks.

In Microsoft Visual Studio 2022 Preview 2, Hot Reload works with many types of apps including those powered by XAML such as WPF and WinUI 3 along with many others including Windows Forms, ASP.NET ...

Microsoft announced the first public preview of Visual Studio 2022. The improved tool will be faster, more lightweight, and will be a 64-bit app.