We develop a novel framework, the implicit hitting set approach, for solving a class of combinatorial optimization problems. The explicit hitting set problem is as follows: given a set U and a family ...

In bioinformatics, multiple sequence alignment (MSA) is an NP-hard problem. Nature-inspired approaches can provide an approximate solution compared to conventional approaches. In this article, the MSA ...

Multiple sequence alignment (MSA) is a cornerstone of computational biology, facilitating the exploration of functional, structural and evolutionary relationships among biological sequences.