The research, done in mice and in human cells, shows that a protein called STUB1 restrains the immune system’s elite ...

A few limited clinical trials of lithium for Alzheimer’s disease have shown some efficacy, but the lithium compounds they ...

At a glance: In a marked advance over current AI models, the new approach captures how proteins act not in isolation but in their cellular and tissue environments. The model illuminates how ...

After a protein attaches to the proteasome, it may tumble between different configurations. The proteasome, in turn, constantly switches its conformation accordingly. These changes create a ...

A Mammoth Solution Scientists look to extinct genes to protect endangered species, climate ...

The answer is clear for a handful of well-known genetic mutations, yet despite dramatic leaps in genome sequencing technology over the past 20 years, our ability to interpret the meaning of millions ...

The female genital tract is naturally colonized by mixed communities of bacteria, known as the vaginal microbiome. When these communities are dominated by species such as Lactobacillus crispatus, the ...

Harvard Medical School scientists have successfully restored vision in mice by turning back the clock on aged eye cells in the retina to recapture youthful gene function. The team’s work, described ...

New AI model identifies possible therapies from existing medicines for thousands of diseases, including rare ones with no current treatments. The AI tool generates new insights on its own, applies ...

Study shows AI improves performance for some radiologists but worsens it for others. Understanding who might benefit from AI and who would not is critical for designing tools that boost human ...

In December 2023, through the development efforts of CRISPR Therapeutics and Vertex Pharmaceuticals, their decades-long endeavor reached fruition in the form of a new treatment, CASGEVY, approved by ...

Wei-Chung Allen Lee is working in a new field of neuroscience called connectomics that aims to comprehensively map connections between neurons. Video: Catherine Caruso, Stephanie Dutchen, and Tyler ...