Cell migration in confined environments leads to nuclear envelope rupture, chromatin leakage and genomic instability. This study identifies the formin DIAPH3 as an inducer of protective nuclear ...
Transition between cell states of sensitivity reveals molecular vulnerability of drug-tolerant cells
Cancer cells evade apoptosis by transitioning between cell states of drug-sensitivity. Necroptosis vulnerability state was ...
BACKGROUND: PYGM (muscle glycogen phosphorylase), the rate-limiting enzyme in glycogenolysis, plays an indispensable role in maintaining cardiac energy metabolism. However, the role of PYGM in the ...
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