Background Anti-C1q autoantibodies can disrupt normal complement function, contributing to the formation of pathogenic immune ...
Background Lupus nephritis (LN) is the most serious complication of SLE. Interstitial fibrosis is the dominant pathological ...
Objective Peer mentoring has been shown to be an effective intervention for chronic conditions with evidence to suggest that ...
Objective To investigate the effects of Qihuang Jianpi Zishen Granules (QJZG) on renal injury in SLE mice, focusing on macrophage M1/M2 polarisation mediated by the AMPK/ULK1 signalling pathway.
Each year the Lupus Science & Medicine editorial team selects the most meritorious research papers to receive the Lupus Science & Medicine Paper of the Year Award. Primary considerations are the ...
Objective To investigate the pharmacokinetics, effectiveness, safety and tolerability of tofacitinib in young adults with active mucocutaneous (MC) SLE manifestations. Methods Patients with SLE and ...
Objective Small fibre neuropathy (SFN) is an under-recognised complication of SLE that contributes to chronic pain and reduced quality of life. We assessed the utility of corneal confocal microscopy ...
Belimumab (BEL) is a monoclonal antibody that selectively binds to BLyS, a survival factor for B cells, while anifrolumab (ANI) is a monoclonal antibody that binds to the type I interferon (IFN) ...
Haematologic involvement in patients with systemic lupus erythematosus (SLE) is very common. The principal cytopenias in lupus result in anaemia, white cell deficits and thrombocytopenia. Anaemia may ...
The 2025 EULAR recommendations for the management of systemic lupus erythematosus (SLE) with kidney involvement followed the EULAR standardized operating procedures, by recruiting an international ...
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