Objective To examine the associations between the number of days per week achieving various daily step thresholds and all-cause mortality and cardiovascular disease (CVD) incidence in older women.

Background Pulmonary hypertension (PH) is a progressive cardiopulmonary condition associated with increased morbidity and mortality. The extracellular matrix component hyaluronan (HA) is linked to ...

Objective To analyse NHS health datasets to estimate the cost of providing emergency adrenaline [epinephrine] autoinjectors (AAIs) to school pupils on a named-patient basis to leave on school premises ...

What should we do in order to improve quality and safety in medicines management? How beneficial is it to design the medicines management system—for example, the tasks, tools and physical ...

Introduction Stroke causes neurological deficits and respiratory dysfunction, with prolonged bed rest exacerbating secondary pulmonary injury. This study evaluated the efficacy of pressure biofeedback ...

Background Minimising hypoxaemia during submaximal walking tests has a positive effect on exercise capacity and dyspnoea in patients with chronic obstructive pulmonary disease (COPD) on long-term ...

Introduction The number of young and middle-aged adult patients with multimorbid and/or complex chronic conditions is rising, presenting challenges for healthcare systems. Advanced practice nurses ...

Importance/background The 12-lead ECG is recommended in clinical guidelines for prehospital assessment of patients with suspected acute coronary syndrome (ACS) presenting to Emergency Medical Services ...

Objectives Youth football players are vulnerable to apophyseal injuries, which can have long-term consequences for health and performance. The objective was to assess the incidence, severity and ...

The clinical and molecular heterogeneity of IBD—both between patients and within the same individual over time—continues to pose a significant challenge to the implementation of truly personalised ...

Background/aim Frequent premature ventricular complexes (PVCs) have historically been regarded as benign in structurally normal hearts, yet emerging evidence suggests substantial cardiovascular risk.

We read with great interest the recent study by Gilliam-Vigh et al demonstrating significant transcriptomic alterations in the intestinal mucosa of individuals with type 2 diabetes (T2D), particularly ...