Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. CD8 + T cells have critical roles in tumor ...

Since pulsed peptides are not covalently linked to MHC-I complexes, it was possible that they might dissociate from the KG-1 cells for subsequent binding and presentation by endogenous WT-A*0201 ...

Tiny tweaks in DNA folding can have big effects. A study from Umeå University shows that even the most subtle changes in DNA's shape have an important influence on gene activity and energy production.

A new discovery inside your cells may change how scientists understand disease and design future treatments. Researchers have found a previously unknown structure in mammalian cells, something they ...

Right now, deep in Southern California’s logistics maze, a fresh Class 8 hydrogen fuel cell truck is revving up for a full-year shakedown that could change the game for zero-emission heavy-haulers. Co ...

The federal government is looking for researchers who can, in 5 years, develop stem cell treatments to repair brain damage caused by stroke, neurodegeneration, and trauma. The Functional Repair of ...

When we think of death, we imagine a final, irreversible end. But what if death is not as absolute as it seems? What if some parts of us — our cells, our tissues — continue to fight for survival, even ...

Bispecific T cell engagers (TcEs) are immunotherapeutic drugs that trigger the destruction of cancer cells by linking T cells to cancer cells through specific surface molecules (antigens). We designed ...

In a major leap forward for genetic and biomedical research, scientists have developed a powerful new artificial intelligence tool that can predict the 3D shape of chromosomes inside individual cells ...

It is well established that cellulose synthesis in higher plants requires three different but related cellulose synthase (CESA) isoforms. Here the authors provide convincing biochemical and cryo ...